Organic Chemistry

These days, we don't have to worry too much about meeting an early demise from ulcers, breaks in the stomach lining that could be fatal back in the early 1900s. This is because we have medicines to treat them, like proton pump inhibitors! In this final episode of Crash Course Organic Chemistry, we'll look at medicinal chemistry by breaking down how penicillin fights bacteria, how proteins are made both in the body and in the lab, and we'll finally finish our synthesis of penicillin V and complete our Mold Medicine Map! Hopefully this series has shown you the many ways organic chemistry is all around us and how it can help us to better understand ourselves, and improve our world! Episode Sources: Patrick, G. L. (2013). An introduction to medicinal chemistry. Oxford university press. Vollmer, W., Blanot, D., & De Pedro, M. A. (2008). Peptidoglycan structure and architecture. FEMS microbiology reviews, 32(2), 149-167. Sauvage, E., Duez, C., Herman, R., Kerff, F., Petrella, S., Anderson,

These days, we don't have to worry too much about meeting an early demise from ulcers, breaks in the stomach lining that could be fatal back in the early 1900s. This is because we have medicines to treat them, like proton pump inhibitors! In this final episode of Crash Course Organic Chemistry, we'll look at medicinal chemistry by breaking down how penicillin fights bacteria, how proteins are made both in the body and in the lab, and we'll finally finish our synthesis of penicillin V and complete our Mold Medicine Map! Hopefully this series has shown you the many ways organic chemistry is all around us and how it can help us to better understand ourselves, and improve our world! Episode Sources: Patrick, G. L. (2013). An introduction to medicinal chemistry. Oxford university press. Vollmer, W., Blanot, D., & De Pedro, M. A. (2008). Peptidoglycan structure and architecture. FEMS microbiology reviews, 32(2), 149-167. Sauvage, E., Duez, C., Herman, R., Kerff, F., Petrella, S., Anderson,

These days, we don't have to worry too much about meeting an early demise from ulcers, breaks in the stomach lining that could be fatal back in the early 1900s. This is because we have medicines to treat them, like proton pump inhibitors! In this final episode of Crash Course Organic Chemistry, we'll look at medicinal chemistry by breaking down how penicillin fights bacteria, how proteins are made both in the body and in the lab, and we'll finally finish our synthesis of penicillin V and complete our Mold Medicine Map! Hopefully this series has shown you the many ways organic chemistry is all around us and how it can help us to better understand ourselves, and improve our world! Episode Sources: Patrick, G. L. (2013). An introduction to medicinal chemistry. Oxford university press. Vollmer, W., Blanot, D., & De Pedro, M. A. (2008). Peptidoglycan structure and architecture. FEMS microbiology reviews, 32(2), 149-167. Sauvage, E., Duez, C., Herman, R., Kerff, F., Petrella, S., Anderson,

These days, we don't have to worry too much about meeting an early demise from ulcers, breaks in the stomach lining that could be fatal back in the early 1900s. This is because we have medicines to treat them, like proton pump inhibitors! In this final episode of Crash Course Organic Chemistry, we'll look at medicinal chemistry by breaking down how penicillin fights bacteria, how proteins are made both in the body and in the lab, and we'll finally finish our synthesis of penicillin V and complete our Mold Medicine Map! Hopefully this series has shown you the many ways organic chemistry is all around us and how it can help us to better understand ourselves, and improve our world! Episode Sources: Patrick, G. L. (2013). An introduction to medicinal chemistry. Oxford university press. Vollmer, W., Blanot, D., & De Pedro, M. A. (2008). Peptidoglycan structure and architecture. FEMS microbiology reviews, 32(2), 149-167. Sauvage, E., Duez, C., Herman, R., Kerff, F., Petrella, S., Anderson,

You might think a self regulating factory sounds pretty unbelievable, but that’s pretty much exactly how our bodies work! Our bodies are full of regulatory mechanisms that keep all the organic molecules we need to live in balance. In this episode of Crash Course Organic Chemistry, we’ll look at the building blocks that form these biological polymers, including carbohydrates, proteins, and DNA! Episode Sources: Garrett, R. H., & Grisham, C. M. (2016). Biochemistry. Cengage Learning. Appling, Dean R., Anthony-Cahill, Spencer J., Mathews, Christopher K.. (2016). Biochemistry: concepts and connections. Essex: Pearson. PDB IDs (available at https://www.rcsb.org/): • 1BNA, 6TNA, 3MQ7, 7BJK, 6EC0, 2D3H, 1UBQ, 1BBB, 3FGU Series Sources: Brown, W. H., Iverson, B. L., Ansyln, E. V., Foote, C., Organic Chemistry; 8th ed.; Cengage Learning, Boston, 2018. Bruice, P. Y., Organic Chemistry, 7th ed.; Pearson Education, Inc., United States, 2014. Clayden, J., Greeves, N., Warren., S., Organic Chemis

You might think a self regulating factory sounds pretty unbelievable, but that’s pretty much exactly how our bodies work! Our bodies are full of regulatory mechanisms that keep all the organic molecules we need to live in balance. In this episode of Crash Course Organic Chemistry, we’ll look at the building blocks that form these biological polymers, including carbohydrates, proteins, and DNA! Episode Sources: Garrett, R. H., & Grisham, C. M. (2016). Biochemistry. Cengage Learning. Appling, Dean R., Anthony-Cahill, Spencer J., Mathews, Christopher K.. (2016). Biochemistry: concepts and connections. Essex: Pearson. PDB IDs (available at https://www.rcsb.org/): • 1BNA, 6TNA, 3MQ7, 7BJK, 6EC0, 2D3H, 1UBQ, 1BBB, 3FGU Series Sources: Brown, W. H., Iverson, B. L., Ansyln, E. V., Foote, C., Organic Chemistry; 8th ed.; Cengage Learning, Boston, 2018. Bruice, P. Y., Organic Chemistry, 7th ed.; Pearson Education, Inc., United States, 2014. Clayden, J., Greeves, N., Warren., S., Organic Chemis

You might think a self regulating factory sounds pretty unbelievable, but that’s pretty much exactly how our bodies work! Our bodies are full of regulatory mechanisms that keep all the organic molecules we need to live in balance. In this episode of Crash Course Organic Chemistry, we’ll look at the building blocks that form these biological polymers, including carbohydrates, proteins, and DNA! Episode Sources: Garrett, R. H., & Grisham, C. M. (2016). Biochemistry. Cengage Learning. Appling, Dean R., Anthony-Cahill, Spencer J., Mathews, Christopher K.. (2016). Biochemistry: concepts and connections. Essex: Pearson. PDB IDs (available at https://www.rcsb.org/): • 1BNA, 6TNA, 3MQ7, 7BJK, 6EC0, 2D3H, 1UBQ, 1BBB, 3FGU Series Sources: Brown, W. H., Iverson, B. L., Ansyln, E. V., Foote, C., Organic Chemistry; 8th ed.; Cengage Learning, Boston, 2018. Bruice, P. Y., Organic Chemistry, 7th ed.; Pearson Education, Inc., United States, 2014. Clayden, J., Greeves, N., Warren., S., Organic Chemis

Although we've spent a lot of time in this series looking at human-made organic chemicals, the term "organic chemistry" was originally used to describe molecules isolated from living things. In this episode of Crash Course Organic Chemistry, we're going back to our roots to learn more about the best synthetic chemists: living things. We'll look at the biochemical building blocks of life from the nitrogenous bases, sugars, and phosphate groups that make up DNA and RNA, to amino acids and lipids, and we'll learn how to convert between Fischer and Haworth projections of carbohydrates. Series Sources: Brown, W. H., Iverson, B. L., Ansyln, E. V., Foote, C., Organic Chemistry; 8th ed.; Cengage Learning, Boston, 2018. Bruice, P. Y., Organic Chemistry, 7th ed.; Pearson Education, Inc., United States, 2014. Clayden, J., Greeves, N., Warren., S., Organic Chemistry, 2nd ed.; Oxford University Press, New York, 2012. Jones Jr., M.; Fleming, S. A., Organic Chemistry, 5th ed.; W. W. Norton & Company

Although we've spent a lot of time in this series looking at human-made organic chemicals, the term "organic chemistry" was originally used to describe molecules isolated from living things. In this episode of Crash Course Organic Chemistry, we're going back to our roots to learn more about the best synthetic chemists: living things. We'll look at the biochemical building blocks of life from the nitrogenous bases, sugars, and phosphate groups that make up DNA and RNA, to amino acids and lipids, and we'll learn how to convert between Fischer and Haworth projections of carbohydrates. Series Sources: Brown, W. H., Iverson, B. L., Ansyln, E. V., Foote, C., Organic Chemistry; 8th ed.; Cengage Learning, Boston, 2018. Bruice, P. Y., Organic Chemistry, 7th ed.; Pearson Education, Inc., United States, 2014. Clayden, J., Greeves, N., Warren., S., Organic Chemistry, 2nd ed.; Oxford University Press, New York, 2012. Jones Jr., M.; Fleming, S. A., Organic Chemistry, 5th ed.; W. W. Norton & Company

Although we've spent a lot of time in this series looking at human-made organic chemicals, the term "organic chemistry" was originally used to describe molecules isolated from living things. In this episode of Crash Course Organic Chemistry, we're going back to our roots to learn more about the best synthetic chemists: living things. We'll look at the biochemical building blocks of life from the nitrogenous bases, sugars, and phosphate groups that make up DNA and RNA, to amino acids and lipids, and we'll learn how to convert between Fischer and Haworth projections of carbohydrates. Series Sources: Brown, W. H., Iverson, B. L., Ansyln, E. V., Foote, C., Organic Chemistry; 8th ed.; Cengage Learning, Boston, 2018. Bruice, P. Y., Organic Chemistry, 7th ed.; Pearson Education, Inc., United States, 2014. Clayden, J., Greeves, N., Warren., S., Organic Chemistry, 2nd ed.; Oxford University Press, New York, 2012. Jones Jr., M.; Fleming, S. A., Organic Chemistry, 5th ed.; W. W. Norton & Company